Depression is frequently observed during perimenopause, though studies haven't established a clear cause-effect relationship between the two. Research indicates a heightened risk of major depressive disorder (MDD) during this phase, which may be influenced by fluctuating hormone levels and their impact on brain chemistry.
Physiological changes, such as declining estrogen levels, can affect neurotransmitters like serotonin and norepinephrine, crucial for regulating mood. Additionally, psychosocial factors such as societal attitudes towards aging and menopause, along with personal stressors and health conditions, may exacerbate depressive symptoms. Treatment options typically involve antidepressants and psychotherapy, tailored to manage both mood disorders and menopause-related symptoms...Read article
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